Symbol
Name
ID

Hcn1
hyperpolarization activated cyclic nucleotide gated potassium channel 1
MGI:1096392

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Human Phenotypes

Microcephaly

Ataxia

Absent speech

Delayed speech and language development

Autistic behavior

Attention deficit hyperactivity disorder

Intellectual disability

Epileptic encephalopathy

Global developmental delay

Seizure

Bilateral tonic-clonic seizure

Generalized non-motor (absence) seizure

Focal-onset seizure

Febrile seizure (within the age range of 3 months to 6 years)

Clonic seizure

Myoclonic seizure

Status epilepticus

Disease(s) Associated with HCN1

developmental and epileptic encephalopathy 24

generalized epilepsy with febrile seizures plus 10

Mouse Phenotypes		abnormal nervous system electrophysiology	abnormal action potential
Availability	Mouse Genotype	abnormal nervous system electrophysiology	abnormal action potential
	Hcn1^tm1.1Lex/Hcn1^tm1.1Lex
	Hcn1^tm2Kndl/Hcn1^tm2Kndl

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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